It has been a big year for artificial intelligence models. For the first time ever, insights enabled by an AI model were deemed sufficiently significant to earn its developers one of the highest accolades in science: the Nobel prize in chemistry. The award jointly honoured the use of AI for protein-structure prediction and protein design. Innovations that underpin machine learning, meanwhile, were awarded the physics prize. Geoffrey Hinton, one of the winners, mused that by assisting mental labour, generative AI might have as big an effect on society as the industrial revolution did by assisting physical labour.